DAVS 2017 Amsterdam, 3 March Dutch Annual Virology Symposium Organizers R.J. de Groot and E.J.H.J. Wiertz LocationCentrale Openbare Bibliotheek (OBA Theater), Oosterdokskade 143, 1011 DL Amsterdam Anja Streefkerk-Veldt +31 (0)30 253 2485 [email protected] Information Programme 09:00 h 09:25 h 09:30 h Welcome Opening Carla Ribeiro Human TRIM5α restricts HIV-1 infection of mucosal Langerhans cells via autophagy 09:50 h Brigitta Laksono The role of infection and depletion of lymphocyte subsets in the pathogenesis of measles-induced immune suppression 10:10 h Anouk Schuren Genome-wide human CRISPR/Cas9 library screen identifies novel players in cytomegalovirus-induced MHC class I degradation 10:30 h Robert Knaap Potent and selective inhibition of Middle East respiratory syndrome coronavirus papain-like protease by engineered ubiquitin variants 10:50 h 11:10 h Coffee Break Roman Koning Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ 11:30 h Franklin Luzia de Nóbrega Understanding inter-species gene exchange and compatibility in a bacteriophage model 11:50 h Charlotte Melia A +RNA virus able to replicate in the absence of membrane modifications 12:10 h Giel Göertz Non-coding subgenomic flavivirus RNA determines virus transmission by mosquitoes 12:30 h 13:30 h Lunch Aartjan te Velthuis Subgenomic viral RNAs link 1918 influenza A virus virulence to RNA polymerase activity 13:50 h Dirk Eggink Polymerase enhancing substitutions that arise during infection with highly pathogenic avian H5N1 influenza in humans 14:10 h Hongbo Guo Dynamics of influenza A virus-receptor interactions 14:30 h 14:55 h Tea Break Francesca Maio Characterization of the interactions between the geminivirus replication initiator protein and the plant factors involved in geminivirus replication 15:10 h Nicholas McCaul The HIV-1 Env signal peptide is a direct contributor to oxidative folding in the ER 15:25 h Werner Ouwendijk Identification of a novel viral transcript that defines varicella-zoster virus latency in human sensory ganglia 15:40 h Joep Joosten The Tudor protein Veneno is essential for viral piRNA production in the vector mosquito Aedes aegypti 16:00 h Beijerinck Virology Prizes Awards Ceremony Opening by Ben Feringa, Board member KNAW 16:05 h Presentation of the Beijerinck Virology Prize 2017 Raul Andino, School of Medicine, University of California at San Francisco, United States Laudatio: Eric Snijder, Jury member M.W. Beijerinck Virology Fund Beijerinck Lecture Rapid co-evolution shaping RNA virus infection Raul Andino 16:50 h Presentation of the Beijerinck Premium 2017 Marit van Gils, Academic Medical Center, Amsterdam, the Netherlands Laudatio: Eric Snijder, Jury member M.W. Beijerinck Virology Fund Beijerinck Premium Lecture Natural infection as a blueprint for rational HIV vaccine design Marit van Gils 17:15 h Closing and Reception