Classificatie van In vivo Inducers van CYP Enzymen

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Classificatie van In vivo Inducers van CYP Enzymen
CYP Enzymen
Sterke Inducers
≥ 80% vermindering in AUC
CYP1A2
CYP2B6
CYP2C8
CYP2C9
CYP2C19
CYP3A
carbamazepine, phenytoine,
rifampicine, Sint Janskruid
Matige Inducers
50-80% vermindering in AUC
Montelukast, phenytoine, roken
Efavirenz, rifampicine
Rifampicine
Carbamazepine,
rifampicine
Rifampicine
Bosentan, efavirenz, etravirine, modafinil,
nafcilline
Zwakke Inducers
20-50% vermindering in AUC
omeprazole, phenobarbital,
Nevirapine
Aprepitant, bosentan, phenobarbital,
Sint Janskruid
Artemisine
Amprenavir, aprepitant, armodafinil,
echinacea, pioglitazon, prednison
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