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Nucleotide Excision DNA Repair Is Associated With AgeRelated Vascular DysfunctionClinical Perspective
by Matej Durik, Maryam Kavousi, Ingrid van der Pluijm, Aaron Isaacs, Caroline
Cheng, Koen Verdonk, Annemarieke E. Loot, Hisko Oeseburg, Usha Musterd
Bhaggoe, Frank Leijten, Richard van Veghel, René de Vries, Goran Rudez, Renata
Brandt, Yanto R. Ridwan, Elza D. van Deel, Martine de Boer, Dennie Tempel, Ingrid
Fleming, Gary F. Mitchell, Germaine C. Verwoert, Kirill V. Tarasov, Andre G.
Uitterlinden, Albert Hofman, Henricus J. Duckers, Cornelia M. van Duijn, Ben A.
Oostra, Jacqueline C.M. Witteman, Dirk J. Duncker, A.H. Jan Danser, Jan H.
Hoeijmakers, and Anton J.M. Roks
Circulation
Volume 126(4):468-478
July 24, 2012
Copyright © American Heart Association, Inc. All rights reserved.
A, Senescence in Ercc1d/− mouse vascular tissue.
Matej Durik et al. Circulation. 2012;126:468-478
Copyright © American Heart Association, Inc. All rights reserved.
Measures of central and peripheral hemodynamics in 8-week-old Ercc1d/− and wild-type (WT)
animals.
Matej Durik et al. Circulation. 2012;126:468-478
Copyright © American Heart Association, Inc. All rights reserved.
Ex vivo vascular function in progeria models and aging models.
Matej Durik et al. Circulation. 2012;126:468-478
Copyright © American Heart Association, Inc. All rights reserved.
Endothelial nitric oxide synthase (eNOS) in aorta and myocardium of Ercc1d/− mice.
Matej Durik et al. Circulation. 2012;126:468-478
Copyright © American Heart Association, Inc. All rights reserved.
Effects of reactive oxygen species scavenging and prevention of endothelial nitric oxide
synthase uncoupling on ex vivo vascular function.
Matej Durik et al. Circulation. 2012;126:468-478
Copyright © American Heart Association, Inc. All rights reserved.
Effect of phosphodiesterase inhibition vinpocetine (Vinpo) on endothelium-independent
vasodilatation.
Matej Durik et al. Circulation. 2012;126:468-478
Copyright © American Heart Association, Inc. All rights reserved.
Mechanical properties of conductive vessels in Ercc1d/−.
Matej Durik et al. Circulation. 2012;126:468-478
Copyright © American Heart Association, Inc. All rights reserved.