ethics of prenatal diagnosis and preimplantation genetic diagnosis

Academic Output
Academic publications/ peer reviewed
2008
Bredenoord, A.L., G. Pennings, H.J.
Smeets, and G. de Wert
Dealing with uncertainties: ethics of prenatal diagnosis and
preimplantation genetic diagnosis to prevent mitochondrial
disorders Hum. Reprod. Update 14(1): 83-94
2008
Pennings G, de Wert G, Shenfield
F, Cohen J, Tarlatzis B, Devroey P
ESHRE Task Force on Ethics and Law 15: Cross-border
reproductive care. Hum Reprod;23:2182-2184.
2008
Smets, E. M., Stam, M. M.,
Meulenkamp, T. M., van Langen, I.
M., Wilde, A. A., Wiegman, A., de
Wert, G. M. and Tibben, A.
Health-related quality of life of children with a positive carrier
status for inherited cardiovascular diseases. American Journal of
Medical Genetics Part A, 146A: 700–707.
2008
Bredenoord AL, Pennings G, de
Wert G
Ooplasmic transfer and nuclear transfer to prevent mitochondrial
DNA disorders: conceptual and normative issues. Hum Reprod
Update 14:669-678.
2008
Bredenoord AL, Dondorp W,
Pennings G, de Die-Smulders CEM,
de Wert G
PGD to reduce reproductive risk: the case of mitochondrial DNA
disorders. Hum Reprod 23:2392-2401
2008
Meulenkamp TM, Tibben A,
Mollema ED, van Langen IM,
Wiegman A, de Wert GM, de
Beaufort ID, Wilde AAM, Smets
EMA
Predictive genetic testing for cardiovascular diseases: Impact on
carrier children. Am J Med Genet Part A 146A:3136–3146.
2009
De Jong A, Berghmans R, De Wert
G
Bescherming van de zwakkeren. MGv 2009; 64:1056-1058
2009
Berghmans R, De Jong J,
Widdershoven G, De Wert G
Dwangmogelijkheden te beperkt. Medisch Contact 2009;64:7780
2009
Pennings G, de Wert G, Shenfield
F, et al
ESHRE Task Force on Ethics and Law 16: Providing infertility
treatment in resource-poor countries. Hum Reprod 2009;24:10081011
2009
Wert, Guido de
Ethics and the Future: Preimplantation genetic testing. In:
Harper J., ed. Preimplantation genetic diagnosis (2nd edition).
Cambridge, 2009, pp.259-273
2009
Dondorp WJ, de Wert G
Fertility preservation for healthy women. Hum Reprod
2009;24:1779-1785
2009
Berghmans R, De Jong J, Tibben A,
De Wert G
On the biomedicalization of alcoholism. Theor Med Bioeth
2009;30:311-321
2009
Olsthoorn-Heim E, de Wert G
Ovarian tissue cryopreservation: promises and uncertainties Eur J
Health Law 2009;16:173-183
2009
Bredenoord A, Dondorp W,
Pennings G, De Die-Smulders C,
De Wert G
Preimplantation genetic diagnosis for mitochondrial disorders:
ethical guidance for clinical practice. Eur J Hum Genet
2009;17:1550-1559
2009
Geraedts JPM, de Wert G
Preimplantation genetic diagnosis. Clinical Genetics 2009;76:315325
2009
De Jong A, Dondorp WJ, De Wert G
Prenatale chromosoomdiagnostiek: breed of smal? Ethische
overwegingen bij het testaanbod. Ned Tijdschr Geneeskd
2009;153:2375-2378
2009
Wert, Guido de
Voorspellend genetisch onderzoek naar de ziekte van
Huntington: ethische aspecten. In: Vervoort, E.L. en Van
Zuuren, F.J., red. De ziekte van huntington en verwante erfelijke
neuropsychiatrische aandoeningen. Van Gorcum, 2009, pp.59-75
2010
Bredenoord AL, Dondorp W,
Pennings G, De Wert G
Avoiding transgenerational risks of mitochondrial DNA disorders:
a morally acceptable reason for sex selection? Hum Reprod.
2010;25(6):1354-1360.
2010
De Jong A, Dondorp WJ, de DieSmulders CEM, de Wert GMWR
De dynamiek van prenatale screening. Medisch Contact 2010; 65:
2006-2010
2010
Bredenoord AL, Dondorp W,
Pennings G, De Wert G
Ethics of modifying the mitochondrial genome. J Med Ethics.
2010 Nov 11. [Epub ahead of print] PubMed PMID: 21071569.
2010
Van der Zande, P., Vermunt, J. D,
Brekelmans, M., Waarlo, A. J.
Expertise development of biology teachers in a community of
practice.
http://projectos.iec.uminho.pt/eridob/ERIDOB_Abstract%20Book
.pdf, p. 162
2010
Dirk Stemerding, Tsjalling
Swierstra, Marianne Boenink
Exploring the interaction between technology and morality in the
field of genetic susceptibility testing: A scenario study. Futures,
Volume 42, Issue 10, pages 1133-1145.
2010
De Jong A, Dondorp WJ, De DieSmulders CEM, Frints SGM, De
Wert GMWR
Non-invasive prenatal testing: ethical issues explored. Eur J Hum
Genet 2010;18:272-277
2010
Bredenoord AL, Dondorp W,
Pennings G, De Wert G
Nuclear transfer to preventmitochondrial DNA disorders:
revisiting the debate on reproductive cloning.Reprod Biomed
Online. 2010 Nov 12. [Epub ahead of print] PubMed PMID:
21169063.
2010
De Wert GMWR, Dondorp WJ
Preconception sex selection for non-medical and intermediate
reasons: ethical reflections. Facts, Views and Visions in ObGyn,
2010, pp. 80-90
2010
Bredenoord AL, Krumeich A, De
Vries MC, Dondorp W, De Wert G
Reproductive decision-making in the context of mitochondrial
DNA disorders: views and experiences of professionals. Clin
Genet. 2010;77(1):10-17
2010
Dondorp WJ, De Wert GM,
Janssens PM
Shared lesbian motherhood: a challenge of established concepts
and frameworks. Hum Reprod. 2010;25(4):812-814
2010
Dondorp WJ, De Wert GMWR
The ‘thousand-dollar genome’: an ethical exploration (Also in
Dutch: Het ‘duizend dollar genoom’: een ethische verkenning.)
Ethics and Health Monitoring Report. The Hague: Health Council
of the Netherlands. Publication no 2010/15E. ISBN 978-90-7882316-2
2011
de Jong A, Dondorp WJ, Frints
SGM, de Die-Smulders CEM, de
Wert GMWR
Advances in prenatal screening: the ethical dimension. Nature
Reviews Genetics 2011; 12, 657-63| doi:10.1038/nrg3036.
2011
Horstkötter, D., Berghmans, R.,
Slatman, J., and de Wert, G.
Biologie en psychiatrie, Ethische aspecten van de preventie van
antisociaal gedrag bij kinderen, [Biology and psychiatry, Ethical
aspects of the prevention of antisocial behaviour in children, in
Dutch] Tijdschrift voor Psychiatrie [Dutch Journal of Psychiatry]
2011
Cornel MC, de Wert G, MeijersHeijboer H
Clinical use of the analysis of the entire genome. Ned Tijdschr
Geneeskd. 2011;155:A2847. Dutch.
2011
Horstkötter, D., Berghmans, R.,
and de Wert, G.
Die Prävention antisozialen Verhaltens bei Kindern: Ethische
Implikationen eines neurobiologischen Ansatzes [The prevention
of antisocial behavior in children: Ethical implications of a
neurobiological approach, in German], Nervenheilkunde, 30 (12),
p.992
2011
Bredenoord AL, Dondorp W,
Pennings G, De Wert G
Ethics of modifying the mitochondrial genome. J Med Ethics.
2010 Nov 11. [Epub ahead of print] PubMed PMID: 21071569.
2011
Dondorp W, de Wert G
Innovative reproductive technologies: risks and responsibilities.
Hum Reprod. 2011 Jul;26(7):1604-8. Epub 2011 Apr 18
2011
ESHRE Task Force on Ethics and
Law, de Wert G, Dondorp W,
Pennings G, Shenfield F, Devroey
P, Tarlatzis B, Barri P, Diedrich K
Intrafamilial medically assisted reproduction. Hum Reprod. 2011
Mar;26(3):504-9. Epub 2011 Jan 19. Review
2011
de Jong A, Dondorp WJ, Frints
SGM, de Die-Smulders CEM, de
Wert GMWR
Non-invasive prenatal diagnosis for aneuploidy: toward an
integral ethical assessment. Human Reprod 2011, doi:
10.1093/humrep/der268.
2011
Bredenoord AL, Dondorp W,
Pennings G, De Wert G
Nuclear transfer to prevent mitochondrial DNA disorders:
revisiting the debate on reproductive cloning. Reprod Biomed
Online. 2011 Feb;22(2):200-7. Epub 2010 Nov 12
2011
Berghmans, R., Horstkötter, D.,
Slatman, J., and de Wert, G.
Onhandelbaarheid als noodlot? [Unruliness as destiny?, in Dutch
] Journaal Ggz en Recht [Journal for Mental Health and Law], 7
(2), p. 48-51.
2011
van der Zee B, de Beaufort I,
Temel S, de Wert G, Denktas S,
Steegers E
Preconception care: an essential preventive strategy to improve
children's and women's health. J Public Health Policy. 2011
Aug;32(3):367-79. doi: 10.1057/jphp.2011.13. Epub 2011 Mar 10
2011
Knoppers BM, Isasi R, Benvenisty
N, Kim OJ, Lomax G, Morris C,
Murray TH, Lee EH, Perry M,
Richardson G, Sipp D, Tanner K,
Wahlström J, de Wert G, Zeng F
Publishing SNP genotypes of human embryonic stem cell lines:
policy statement of the International Stem Cell Forum Ethics
Working Party. Stem Cell Rev. 2011 Sep;7(3):482-4.
2011
de Jong A, Dondorp WJ,
Timmermans DRW, van Lith JMM,
de Wert GMWR
Rapid Aneuploidy Detection or karyotyping? Ethical reflection.
European Journal of Human Genetics (2011) 19, 1020–1025,
doi:10.1038/ejhg.2011.82
2011
de Jong A, Dondorp WJ, de Wert
GM
Rapid aneuploidy screening. Hong Kong Med J 2011; 17(2): 165.
2011
Berghmans, R., Horstkötter, D. and
de Wert, G.
The place of emotions in capacity assessment, American Journal
of Bioethics, Neuroscience 2 (3), p. 66-68.
2012
Horstkötter, D., Berghmans, R., de
Ruiter, C., Krumeich, A., and de
Wert, G.
“We are also normal humans, you know?” Views and attitudes of
juvenile delinquents on antisocial behaviour, neurobiology and
prevention, International Journal of Law and Psychiatry 35 (2012)
289–297
2012
Wybo Dondorp, Birgit SikkemaRaddatz, Christine de DieSmulders, Guido de Wert
Arrays in postnatal and prenatal diagnosis: An exploration of the
ethics of consent Human Mutation Special Issue: Focus on CNV
Detection with Diagnostic Arrays Volume 33, Issue 6, pages
916–922, June 2012 Article first published online: 4 APR 2012
DOI: 10
2012
Boonekamp J, Berghmans R,
Dondorp W, de Wert G
Care for addicted, pregnant women: justification for pressure and
coercion. Tijdschrift Voor Psychiatrie [2012, 54(3):257-266].
2012
Kristien Hens, Wybo Dondorp,
Guido de Wert
Embryos without secrets: An expert panel study on
comprehensive embryo testing and the responsibility of the
clinician. Eur J Med Genet. 2013 Feb;56(2):67-71. doi:
10.1016/j.ejmg.2012.10.013. Epub 2012 Nov 3.
2012
W. Dondorp G. de Wert, G.
Pennings, F. Shenfield, P. Devroey,
B. Tarlatzis, P. Barri and K.
Diedrich et al
ESHRE Task Force on Ethics and Law, Oocyte cryopreservation for
age-related fertility loss† Hum. Reprod. (2012) 27 (5): 1231-1237.
doi: 10.1093/humrep/des029, First published online: February 21,
2012
2012
H. Mertes, G. Pennings, W.J.
Dondorp and G.M.W.R. de Wert
Financial compensations for oocyte donors: soon to be a debate
of the past? Hum. Reprod. (2012) 27 (suppl 2): ii32-ii34. doi:
10.1093/humrep/27.s2.21
2012
Heidi Mertes, Guido Pennings,
Wybo Dondorp and Guido de Wert
Implications of oocyte cryostorage for the practice of oocyte
donation. Hum. Reprod. (2012) 27 (10): 2886-2893.doi:
10.1093/humrep/des250. First published online: July 15, 2012
2012
Marleen Schoonen, Boukje van der
Zee, Hajo Wildschut, Inez de
Beaufort, Guido de Wert, Harry de
Koning, Marie-Louise Essink-Bot,
Eric Steegers
Informing on prenatal screening for Down syndrome prior to
conception. An empirical and ethical perspective. Am J Med
Genet A 158A(3):485-97 (2012), PMID 22302760
2012
Guido M. W. R. De Wert, Wybo J.
Dondorp, Bartha M. Knoppers
Preconception care and genetic risk: ethical issues. Journal of
Community Genetics, July 2012, Volume 3, Issue 3, pp 221-228
2012
Ros Hastings, Guido de Wert, Brian
Fowler, Michael Krawczak, Eric
Vermeulen, Egbert Bakker, Pascal
Borry, Wybo Dondorp, Niels
Nijsingh, David Barton, Jörg
Schmidtke1, Carla G van El, Joris
Vermeesch, Yrrah Stol, Heidi
Carmen Howard and Martina C
Cornel
The changing landscape of genetic testing and its impact on
clinical and laboratory services and research in Europe, European
Journal of Human Genetics (2012) 20, 911–916;
doi:10.1038/ejhg.2012.56; published online 28 March 2012
2012
A Thorogood, BM Knoppers, WJ
Dondorp, GMWR de Wert
Whole genome sequencing and the physician, Clin Genet 2012:
81: 511-513; doi 10.1111/j.1399-0004.2012.01868.x
2012
A Thorogood, BM Knoppers, WJ
Dondorp, GMWR de Wert
Whole-genome sequencing and the physician. Clinical Genetics
Volume 81, Issue 6, pages 511–513, June 2012. Article first
published online: 9 APR 2012. DOI: 10.1111/j.13990004.2012.01868.x
2012
J. Boonekamp, R. Berghmans, W.
Dondorp, G. de Wert
Zorg voor verslaafde zwangere vrouwen: rechtvaardiging van
drang en dwang. Tijdschrift voor Psychiatrie 54 (2012) 3, 257 –
266
Academic publications/ other
2011
de Jong A, Dondorp WJ, de Wert
GMWR
Ethical issues in prenatal and neonatal screening. In: Wildschut
HIJ, van Goudoever JB, den Hollander NS, de Wert GMWR (eds).
Foetal and neonatal screening. Methods and results. Amsterdam,
Reed business. 2011: 405-438. (In Dutch)
Academic lectures/ invited
2008
Wert, Guido de
Embryo selection: ethical reflections. Maastricht, January 11,
2008
2008
Wert, Guido de
Prenatal screening: dynamics and ethics. Amsterdam, March 14,
2008
2008
Wert, Guido de
Preimplantation microarray screening: a Gordian knot.
Barcelona, July 8, 2008
2008
Wert, Guido de
Microarray screening in IVF: ethical issues. Interview BBC, July
9, 2008
2008
Wert, Guido de
Behavioral genomics: ethics and policy. Amsterdam, December
11, 2008
2010
Wert, Guido de
Chairman Workshop ‘The $1000 Genome: normative issues’
/Satellite Congress Eur Soc Hum Genet 11 June 2010,
Gotheburg
2010
Wert, Guido de
Treating the embryo. Congress Dialogue Christian/Muslim World,
22 November, Amsterdam
2011
de Wert, G.
Widening the scope of NIPD-based prenatal screening: the ethics
of predictive testing of (future) children. Pre-congress Course of
the Special Interest Group Ethics and Law at the Annual
Congress of the European Society of Human Reproduction and
Embryology (ESHRE). Theme: Ethical aspects of non-invasive
prenatal diagnosis (NIPD). Stockholm, 3-6 July 2011.
Academic lectures/ peer reviewed
2010
Wert, Guido de
Preimplantation genetic diagnosis: ethical analysis. Congress
European Society of Human Reproduction and Embryology
(ESHRE) on PGD, Rome, 1 July 2010
2010
Wert, Guido de
Whole genome analysis in potenatal testing: dynamics and
ethics. Congress International Federation of Fertility Societies
(IFFS), 13 September 2010, Munich
2010
Wert, Guido de
Ethics of Gamete Donation. Congress Dutch Society on
Reproductive Medicine (DSRM), 3 December 2010.
Academic lectures/ other
2011
de Wert G., Dondorp W.
How to deal with unexpected findings/ informed consent. Precongress Course at the Congress of the European Society of
Human Genetics (ESHG). Theme: Array in daily practice:
promises and pitfalls. RAI, Amsterdam, 27 May 2011
Societal Output
Societal publications
2008
Wert, Guido de
Embryo selection: ethics and policy. NRC, July 1, 2008
2008
Wert, Guido de
Ethics of whole genome preimplantation screening. Interview
NRC, Science Section, November 15-16, 2008.
2009
Wert, Guido de and Ron
Berghmans
Neem zwangere verslaafde vroeger op. Opiniepagina NRC 29
Jan. 2009
2009
Dondorp, Wybo and Guido de Wert Een slimme meid vriest haar eicellen in. Opiniepagina NRC 14
May 2009
2010
Dondorp, Wybo, Antina de Jong en Echo zorgt voor onverwachte dilemma’s. NRC 16 februari 2010
Guido de Wert
2010
Dondorp, Wybo, Antina de Jong en Echo is bedoeld om ouders te helpen. Trouw 9 maart 2010
Guido de Wert
2010
Wert, Guido de en Wybo Dondorp
Klink is te huiverig voor screenen op taaislijmziekte. NRC 18 juni
2010
2010
Wert, Guido de
Interview on ‘The $1000 Genome’, NRC 31 December 2010
2010
de Jong A. Dondorp WJ, de DieSmulders CEM, de Wert GMWR
Responding Letter. Medisch Contact 2010; 65 (46). (In Dutch)
2011
Berghmans, R., Horstkötter, D, and (25-11-2011) Potentieel asociale kleuter zit al in de
de Wert, G
beklaagdenbank [Potentially antisocial pre-schooler lands in the
dock], de Volkskrant [authors put in alphabetical order].
2011
de Wert GMWR
Gentechnologie van wieg tot graf. LEV Magazine, 2011; 6:9-12.
(In Dutch)
2011
de Jong A. Dondorp WJ, de Wert
GMWR.
Letter on early foetal ultrasound scan. Medisch Contact 2011;
29/30: 1860-1861. (In Dutch)
Societal lectures
2011
De Wert G.
Prenatal diagnosis and embryo selection. Medical-ethical
dilemmas Lecture series. Studium Generale Maastricht
University, 26 April 2011